Let's identify niches! Places to start Transhuman Space Campaigns

[Astromancer]

What it says on the tin. This thread is all about finding narrow enough areas within the THS setting to start a campaign. Bonus points for logical means to expand later on in the campaign narrative.

Law enforcement and crime strike me as rich sources of niches. All you need is to pick a place that lets the GM use the diversity of the setting without drowning the PCs.

Plenty of neighborhoods in THS London, L.A., New York, or Sydney, would achieve this. Law enforcement on the less populated areas of the Moon would give you space adventure and gritty crime drama.