[DF] Risky Potions

[Bruno]

The Backlash and Nuisance Effect limitations for advantages may be a source of ideas and how much to reduce prices by - a Strength potion that makes you glow brilliantly would be a minor problem, while a Strength potion that gives you Severe Pain while the effect is active would be a huge problem.

A Healing potion that makes you sleepy or exhausted (costs 2d FP to use)?

Any buffing potion that doesn't sit well on the stomach, making the character Nauseated for an hour, would be a difficult choice for most PCs.

You could require the PCs to make a HT roll (at a bonus or a penalty) to resist the negative side effects - let Resistant to Metabolic Hazards give a bonus on this, as well as Magic Resistance and any other resistance you can think of applying. Races with HT bonuses, Fit (which gives a bonus to HT rolls), and relevant resistances will usually not suffer the side effects, while less robust races and characters will. Goblinoids are an obvious choice for creating these types.

Races with High Pain Threshold will sneer at Pain effects, or at least be less penalized by them. Races with a strong "warrior culture" stereotype will endure them as proof that they are "tough".