Quote:
Originally Posted by Varyon
I don't know about the availability outside of the US, but the .454 Casull is also in the same range (High Tech gives it 5d-1 pi+). An advantage to the .454 Casull is that weapons chambered for it can also use the much more common .45 Long Colt and .45 S&W without issue. Which means, if your monster-hunting rounds (probably hand-loaded match-grade +P, potentially HP/Poison rather than FMJ) are a precious commodity, you can opt to generally use more common (but less powerful) ammunition most of the time, only switching to your special rounds when needed. From the few examples in HT, .45 Long Colt will deal around 3d-2 pi+, while .45 S&W will deal around 2d-1 pi+.
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It's unnecessarily hard to engineer semi-automatic pistols to use revolver rounds and tends to play havoc with reliability. I don't think anyone has ever used a Desert Eagle for a more useful purpose than playing at a firing range, but I'd bet that the .357 Magnum chambered version jammed more than the later versions which dispensed with the rimmed revolver rounds.
Besides, you already have the .45 Winchester Magnum for automatic pistols. If you're absolutely determined to have more power, more blast, more flash, more noise and more recoil than a person could reasonably want, you could also custom-make a semi-automatic pistol in .450 Bushmaster or even 45 Raptor (basically just a .460 S&W Magnum without a rim, so that is can be chambered in a semi-automatic firearm, albeit for sane people, in a semi-automatic
rifle). ;-)