440 Cor-Bon Ammo for a Desert Eagle

[Kesendeja]

In the "Monster Hunter" game I'm running the player wants a gun big enough to get through bio-engineered and/or demonic opposition, or god forbid something that's both. (think Resident Evil meets Devil May Cry). The Desert Eagle fits the bill nicely. But doing a little reaserch I found this:

.440 Cor-Bon Ammunition

"this cartridge was designed after being necked down from an existing cartridge, the .50 AE to accept a .44-caliber (.429 in) (10.89 mm) bullet."

"Its excessive penetration and recoil make it unsuitable for self-defense, it is a physically larger cartridge, commonly chambered in a large pistols such as the Desert Eagle"

I was wondering if using ammunition like this would change the damage of the gun. I was thinking it would up the damage to p++? or give it an armor divisor of half?

Opinions welcome.