Re: [Space] Interactions between species
Not to push my own work, but I provided a fairly extensive write-up for the Sector General series of books, which includes lots of material on how very different species - with different Sizes, home gravities, atmospheres, etc. - interact.
It includes "crunchy" rules on using and adapting alien tools which you might find useful. Do a search for "GURPS Sector General" on this board.
If you want written material with good ideas for how very different species interact, in addition to James White's "medical space opera-lite" take on the subject in his Sector General books, David Brin's Uplift series is also excellent while leaning towards hard SF.
There were two editions of GURPS 3E Uplift published, which might be worth checking out if you can find a used copy. The second edition is more comprehensive, but the first edition has a bit more rules crunch, which was later incorporated into GURPS 4E material.
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