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Originally Posted by Johnny1A.2
It all depends on what you're trying to do with the brain-in-a-jar. (I'm actually skeptical of this because I don't think the brain is set up to work very well in such isolation, but allowing for that, there's also the risk that the brain-in-a-jar might have his or her own ideas about function and role...
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I like the horror aspect of the brain, the very center of who we are, being stolen and perverted for nefarious purposes, but it's a little more super-sciency than I intend to go in my campaign. Still, if I were to go there, I'd explain it as the brain being basically lobotomized to (mostly) eliminate agency and personality, and only interface with the parts that enable cognition, language, sarcasm and humour detection, etc. Effectively using the brain as some sort of BPU (biological processing unit), like a GPU for graphics, only for things humans can do better than machines.