Playing cards in response to a "Discard All" curse?

[MunchkinMan]

To be very clear: You can't normally play cards in response to anything in Munchkin. It doesn't use a stack-based card play mechanic and once a card is played, it's resolved and then discarded or remains in play, depending on the card's purpose. If you're affected by a Curse, you resolve the Curse immediately. Only cards that say they cancel something can actually be played before resolving what's to be canceled, since that's the cancelling card's purpose.