[AlexanderHowl]

It really does depend on the setting, as Social Stigma (Monster) may be more appropriate. In any case, you may want to decide how animal the individual species are (their traits) and how anthropomorphic the individual species are (especially when it comes to sex and reproduction).

For example, one catgirl species could have the advantages of Appearance (Attractive) [4] and Night Vision 5 [5] and the features of Cat Ears and Purr while another catgirl species could be a 150+ CP combat species. In the either case, they are likely sexually compatible with humans (though Erotic Art would likely suffer Physiology penalties), though they are unlikely to be reproductively compatible with humans (magic and/or technology may circumvent those restrictions however).