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Originally Posted by sir_pudding
Which seems off, because Robocop's brain dies if he runs out of paste to eat. I suppose that could be Machine and Dependency (Nutrient paste) though.
On the other hand, AI-guy can still be rebooted even if he was in a bioshell, which wouldn't have Machine.
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These are two halves of the same problem: it's technically possible to have a machine brain in a bio body, or a bio brain in a machine body, and it's possible to have a digital mind running on a biobrain (this is explicitly stated on B48).