As a general rule, we prefer not to have a lot of unrelated questions in a single post. However, your questions are quick, so I'm going to answer them rather than split this up.
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Originally Posted by Talon23
1. After kicking door if you get a curse do you still get to loot the room or look for trouble?
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Yes, you can loot/look for trouble following a Curse.
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Originally Posted by Talon23
2. If you do not find a monster when kicking down the door but do when you loot the room do you still get to play the mister or one from your hand after looting?
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Looting the Room means you cannot Look for Trouble that turn. It's one or the other.
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Originally Posted by Talon23
3. When fighting multiple monsters do you fight them separate or do you add their total against yours? When someone plays a one shot against these does it go towards a specific monster or the group as a whole?
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Monsters fight you together; you have to beat their combined combat strength. Monster Enhancers (the cards that say "-5/+5/+10 to Monster") apply to a specific monster; other bonuses apply to the monster side collectively.
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Originally Posted by Talon23
4. When getting help can more than one person add their combat level? If not, is there a limit to how many people that could play one shot items to help you win?
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Only one person gets to join the combat as a helper. Anyone may play one-shot cards to help either side.
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Originally Posted by Talon23
5. When playing a one shot item do you get to direct whether it goes towards the monster or munchkin? Or does it always go towards munchkin unless it says you get to pick?
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The person playing the card chooses which side to help.
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Originally Posted by Talon23
6. Can you only trade items?
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Yes, and only Items in play.
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Originally Posted by Talon23
7. When can you apply a card to the table to be in play like a race or class? Does it have to be during your turn or after? At the beginning of the game do you have to wait till your turn to put cards down?
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You can play a Race or Class as soon as you get the card, or at any time on your turn. Everyone has a chance to play cards before the game officially gets underway; you don't have to wait until your turn.
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Originally Posted by Talon23
8.Can one shot items be kept on table?
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Yes.
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Originally Posted by Talon23
9.Can you fight one monster and flee the others? Or are they all together? This concept is confusing to me..
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No, they stick together. If you can't beat them all, combined, you have to Run Away from each monster.
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Originally Posted by Talon23
10. What cards can be kept in front of you on the table?
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As a general rule, and noting that there are some exceptions in specific sets: Your active Class and Race cards (plus Super Munchkin and Half-Breed). Items (any cards with a Gold Piece value printed on them), as long as you only have one Big item on the table. Some special Treasure cards such as Really Impressive Title that look like permanent Items can also be played on the table. Cheat! is played with an Item. Hireling can be played with an Item or on its own, and you can change out the Item that goes with it when you feel like.
Cards you cannot keep in play: Spare Class and Race cards. Monsters. Monster Enhancers. Wandering Monster. Curses (unless it is a Curse with an ongoing or upcoming effect, kept out as a reminder). Super Munchkin or Half-Breed without a Class or Race card, respectively. Cheat! without an Item card.