Try this idea...
This is only part of a setting, but a good place to set adventures. I think that most successful sci-fi and/or fantasy TV shows then to be built around either a place or group that goes everywhere (Star Trek's Enterprise, Doctor Who's Tardis) or a place that everyone comes to (The Babylon5 station in Babylon5, Sunnydale in BtVS). What this setting is built around is the latter. The setting is the orbital end of Earth's
Beanstalk.
By its nature, the setting is the point of contact between Earth and the Solar System. I see this as being in a setting like
THS or something similar. Earth is the center of the Human Universe. If interstellar travel exists, extrasolar worlds are frontiers or exotic and alien in the same way China was in Marco Polo's day.
in some ways, this setting would be like 19th century Hong Kong, Jakarta, or Singapore, or 18th Century Nagasaki, the gate into an exotic and ancient world. Like 19th century New Orleans, St. Louis, or Melbourne, the gate to the frontier. It depends on which direction the PC is traveling. If you think of
Robert Louis Stevenson idea of London as "Baghdad on the Thames!" then you've got an idea of what to go for.
Pcs could also play staff or residents of the station. Dealing with all the opportunities and problems such a gateway local would bring.