[AlexanderHowl]

Cradle-1

A mutation in the syphilis bacteria around 1800 caused sterilty in any infected man rather than disfigurement and death while infected women were just carriers (transmitting their mutant syphilis to their children during birth). By 1900, the population of the Earth had decreased by 90% due to the spread of the mutant syphilis strain. Other than a few dozen isolated tribes, the human population of the Earth faces extinction within a century.