[Palmer]

One option to simplify the game and keep "Who's turn?" confusion down is simple. No response rolls, and no going around the table for turns.

Caster targets and rolls.
Apply effects.
Now it's the target's turn.
Repeat.

It's easy to track turns, and balances out. You might say some people don't get as many turns, but they're also not being attacked as often. Someone who never gets a turn will most likely win, because they could only have lost sanity to Cthulhu, while everyone else is losing it to everything.

This also eliminates the response-tentacle confusion.